Fenretinide, a retinol inhibitor, slowed progression of dry AMD and prevented the development of choroidal neovascularization in a phase 2 study of geographic atrophy. Jason Slakter, MD, reported these results at the annual meeting of the American Academy of Ophthalmology, October, 2010. Fenretinide halts the accumulation of a toxic byproduct of Vitamin A in the photoreceptors of the retina. It also inhibits proteins that cause increased vessel growth, leading to bleeding in the retina. A phase 3 trial will begin in 2011.